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KMID : 0812020060120010012
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Korean Journal of Neurogastroenterology and Motility
2006 Volume.12 No. 1 p.12 ~ p.18
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Clinical Spectrum of Endoscopic Reflux Esophagitis in Routine Check-Up Subjects in Korea
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Oh Jung-Hwan
Choi Myung-Gyu
Han Sok-Won
Chung In-Sik
Kim Sang-Woo
Lee In-Seok
Jeon Eun-Jung
Paik Chang-Nyol
Park Jae-Myung
Cho Yu-Kyung
Jeong Jeong-Jo
Choi Sang-Wook
Kim Hye-Rang
Lee Joon-Wook
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Abstract
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Background/Aims: As little is known about asymptomatic patients with erosive reflux esophagitis, this study aimed to evaluate the characteristics of subjects with erosive reflux esophagitis who were diagnosed by endoscopy in a routine health check-up program.
Methods: We prospectively recruited the subjects who had erosive reflux esophagitis (≥LA grade A) among those who visited a health promotion center for routine check-up. We performed a case-control study to evaluate the clinical characteristics and risk factors of reflux esophagitis.
Results: The enrolled study participants comprised 264 subjects with erosive reflux esophagitis and 245 healthy controls. All subjects with erosive esophagitis had LA grade A (85%) or B (15%). Eighty percent of all subjects (N=264) with erosive esophagitis did not have frequent reflux symptoms. Using a multiple logistic regression analysis, erosive reflux esophagitis was associated with smoking (odds ratio (OR), 2.8; 95% confidence interval (CI), 1.7-4.4), and BMI (OR, 1.2; 95% CI, 1.1-1.3). Subjects with symptomatic erosive esophagitis had higher psychosomatic symptom scores than asymptomatic subjects did.
Conclusions: Only 20% of subjects who were diagnosed with erosive esophagitis at their routine check-up had frequent reflux symptoms. Symptomatic erosive esophagitis was associated with psychological factor.
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KEYWORD
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Gastroesophageal reflux disease, Reflux esophagitis, Psychological factor
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